
START HERE
The Big Picture
The introductory overview of the complete six-mechanism framework and how the mechanisms interact.
COMING SOONDr. Robert Groysman, MD
Discover the upcoming Long COVID Umbrella series and explore Dr. Groysman's currently published Long COVID handbooks.
UPCOMING SERIES
Long COVID Umbrella is Dr. Robert Groysman's upcoming mechanism-based book series covering the six major interacting mechanisms of Long COVID. Begin with The Big Picture, the introductory overview of the complete framework.

START HERE
The introductory overview of the complete six-mechanism framework and how the mechanisms interact.
COMING SOONAn upcoming guide to the autonomic nervous system mechanism within the Long COVID framework.
COMING SOONAn upcoming guide to the cellular energy mechanism within the Long COVID framework.
COMING SOONAn upcoming guide to the gut microbiome and intestinal barrier mechanism within the Long COVID framework.
COMING SOONAn upcoming guide to the mast cell and histamine mechanism within the Long COVID framework.
COMING SOONAn upcoming guide to the vascular mechanism within the Long COVID framework.
COMING SOONAn upcoming guide to the hormonal and metabolic mechanism within the Long COVID framework.
COMING SOONCURRENTLY AVAILABLE
Dr. Groysman's currently published Long COVID handbooks remain available while the expanded Long COVID Umbrella series is being developed and released.
2nd Edition, Foundation Volume
The foundation volume. Maps all six biological mechanisms to symptoms, triggers, and treatment frameworks. The essential starting point for patients and clinicians.
Volume 2
When the autonomic nervous system fails to regulate heart rate, blood pressure, and basic bodily functions, the result is a cascade of symptoms that most doctors miss entirely.
Volume 3
Profound fatigue, post-exertional malaise, and cognitive impairment often trace back to impaired ATP production at the cellular level. This volume explains why, and what to do.
Volume 4
A disrupted gut microbiome drives systemic inflammation, nutrient malabsorption, and multi-system symptom amplification. The gut-brain axis is rarely addressed, but often central.
Volume 5
Unpredictable reactions to foods, medications, and environmental triggers. Mast cell activation syndrome is one of the most common and most overlooked mechanisms in Long COVID.
Volume 6
Damaged vessel linings and microclot formation restrict oxygen delivery throughout the body. This vascular mechanism explains symptoms that don't respond to conventional treatment.
Volume 7
Disruptions in testosterone, estrogen, thyroid, and cortisol compound fatigue, mood dysregulation, and metabolic dysfunction. Often the missing piece in an incomplete treatment plan.
Prefer the complete collection? Get all seven currently published handbooks together.
Get the Complete BundleMore from Dr. Groysman
A two-volume guide to help patients map their symptoms to the mechanisms behind them.
Brain fog, poor sleep, fatigue, and nervous system symptoms can feel like separate problems. This series helps you recognize patterns, connect symptoms, and understand the biological mechanisms that may be contributing, all in plain language. Designed for patients with or without Long COVID, these books help you make sense of what you are experiencing and have more informed conversations with your healthcare provider.
Explore the volumes →Best for patients whose body can no longer recover normally.
For patients who crash, flare, or relapse after ordinary physical, mental, or metabolic stress. The focus is not just describing symptoms, but helping you understand why your recovery system became fragile and how to rebuild capacity without triggering more setbacks.
Coming soon